Bromadiolon

1,Bromadiolone is a potent rodenticide. 2,CAS No.:28772-56-7 3,purity 95%,98%TC 4,Formulation:Concentration Liquid

Physical characteristics:

The technical material (97% pure) is an odourless, yellow-white powder. A mixture of the two diastereoisomers melts at 200 -210 ºC.

Vapour pressure:

Negligible (0.002 mPa at 20ºC).

Pests controlled:

Rats and mice, including those resistant to first generation anticoagulants.

Use pattern:

To be used in tamper-proof baited traps filled with sufficient fresh bait to provide an uninterrupted supply for 10-15 days. Concentrated products should be diluted with bait material as directed by the manufacturer. May be used in permanent bait stations or used periodically. May be used outdoors, in non-food storage areas and in food processing plants, but only where food or feeds, their handling equipment or packaging materials are never open or exposed.

Mode of action:

Bromadiolone is vitamin K antagonist. The main site of its action is the liver, where several of the blood coagulation precursors under vitamin K dependent post translation processing take place before they are converted into the respective procoagulant zymogens. The point of action appears to be the inhibition of K1 epoxide reductase.

Precautions in use:

Bromadiolone is an anticoagulant, highly toxic to rodents and highly toxic to other mammals. A lengthening of the blood clotting time may be seen after ingestion or dermal absorption of the compound. The action is a specific inhibition of prothrombin synthesis and can be effectively counteracted by vitamin K1. The low concentration of bromadiolone present in most formulations decreases the hazard of these products and symptoms may not be present following exposure.

Bromadiolon